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Sunday, March 17, 2024

Intralipid Therapy

Intralipid Infusion Therapy during IVF

In 2011, a group of curious UK researchers administered intralipid infusions to a group of fifty infertile women. One thing that these women had in common was the fact that all of them had undergone a number of failed IVF cycles. At the end of this trial, half of the wpmen got pregnant after taking intralipids. The miscarriage rate was higher for the group who weren’t given intralipids (this was the control group). Even though this was a relatively small study, it aroused interest among fertility specialists to see whether intralipid infusion could possibly improve clinical pregnancy rates after IVF and also possibly minimize the risk of miscarriages?

Intralipid infusion therapy is a short term treatment administered before and after IVF treatments for specific patient groups. If you have suffered from recurrent (repeated miscarriages) or repeated IVF failures, then there is a chance that you may test positive for a high number of natural killer cells.

Intralipid Infusion Therapy during IVF

In 2011, a group of curious UK researchers administered intralipid infusions to a group of fifty infertile women. One thing that these women had in common was the fact that all of them had undergone a number of failed IVF cycles. At the end of this trial, half of the wpmen got pregnant after taking intralipids. The miscarriage rate was higher for the group who weren’t given intralipids (this was the control group). Even though this was a relatively small study, it aroused interest among fertility specialists to see whether intralipid infusion could possibly improve clinical pregnancy rates after IVF and also possibly minimize the risk of miscarriages?

Intralipid infusion therapy is a short term treatment administered before and after IVF treatments for specific patient groups. If you have suffered from recurrent (repeated miscarriages) or repeated IVF failures, then there is a chance that you may test positive for a high number of natural killer cells.

Natural killer cells are a type of white blood cells that help contain viral infections. Presence of a high number of natural killer cells can signal to your body to treat an implanting embryo as an invading cell or a foreign object and therefore attack it. This suggests that you may have an overactive immune system which may need to be suppressed.

Intralipid is a synthetic mixture which consists 10% soybean oil, 1.2% egg yolk phospholipids, 2.25% glycerin and water. It is administered
through an IV drip on the arm. The purpose of intralipid infusion is to lower the activity of natural killer cells, and therefore, reduce the likelihood of an implantation failure caused by the presence of natural killer cells.

Who needs Intralipid Infusion?
Couples with repeated IVF failures or recurrent miscarriages will be referred to a lab to test for presence of natural killer cells. This will be done via a blood test and depending on your test result, your suitability for intralipid infusion therapy will be assessed. If you have tested positive for high level of natural killer cells, then we will make the necessary arrangements so that your intralipid infusion can be scheduled during your treatment in Cyprus.

How much does Intralipid Infusion Cost?
Intralipid infusion requires a few sessions during your IVF treatment. Ideally, two sessions will be administered in order to minimize the risk of an implantation failure. If your pregnancy test is positive, then you will need a few more infusions possibly up to the 20th week of your pregnancy in order to prevent elevation of natural killer cells. The infusions at our clinic during your cycle cost 500 Euros. The cost of follow up infusions in your local country will vary depending on where you choose to receive this service.

How long does the treatment take?
The treatment with intralipid infusion takes a little more than an hour. You will be resting during this procedure. The iv drip is painless and you should not feel any discomfort during the procedure. The only minor pain you will feel is when the cannulla is placed in your arm to allow the flow of drip into your bloodstream. If you are having an intralipid drip for the first time, the length of therapy will be longer in order to avoid an allergic reaction to the contents of the drip. You should expect to spend about 2-3 hours at the clinic.

Based on our own clinical experience, we can say with confidence that quite a substantial number of women have gone on to carry pregnancy to a full term after being treated with intralipid infusion during their IVF treatment (along with other supplementation). For women with elevated natural killer cell presence and women with repeated IVF failures and/or recurrent miscarriages, intralipid infusions will be a part of our treatment regimen.

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