{"id":3615,"date":"2020-01-15T14:01:34","date_gmt":"2020-01-15T14:01:34","guid":{"rendered":"https:\/\/www.lowcostivf.net\/?p=3615"},"modified":"2020-03-22T22:58:31","modified_gmt":"2020-03-22T22:58:31","slug":"stem-cell-therapy-for-patients-suffering-from-non-obstructive-azoospermia","status":"publish","type":"post","link":"https:\/\/www.lowcostivf.net\/tr\/latest-news-from-north-cyprus-ivf-center\/stem-cell-therapy-for-patients-suffering-from-non-obstructive-azoospermia\/","title":{"rendered":"Obstr\u00fcktif Olmayan Azoospermiden \u015eikayet\u00e7i Olan Hastalarda K\u00f6k H\u00fccre Tedavisi"},"content":{"rendered":"<h2 class=\"wp-block-heading\"> Sperm \u00dcretimi \u0130\u00e7in K\u00f6k H\u00fccre Tedavisi?<\/h2>\n\n\n\n<p><strong>T\u0131kanmayan azospermi<\/strong> benzer bir sonuca yol a\u00e7an bir grup sorunu i\u00e7erir: Sperm \u00fcretimi\/olgunla\u015fmas\u0131 eksikli\u011fi. Bir sperm h\u00fccresinin \u00fcretimi ve olgunla\u015fmas\u0131 ile ilgili t\u00fcm s\u00fcre\u00e7lerin toplam\u0131 i\u00e7in kullan\u0131lan bir terim olan spermatogenez, birden fazla ad\u0131mdan olu\u015fur. Bu ad\u0131mlardan herhangi biri s\u0131ras\u0131ndaki herhangi bir ar\u0131za, ejak\u00fclatta olgun bir sperm h\u00fccresi elde edilmesinde sorunlara neden olabilir. Bu a\u015famalar kabaca Mitoz (germ h\u00fccrelerinin kopyalanmas\u0131), mayoz 1, mayoz 2 ve son farkl\u0131la\u015fma olarak kategorize edilebilir. T\u00fcm s\u00fcrecin tamamlanmas\u0131 yakla\u015f\u0131k 65-70 g\u00fcn s\u00fcrer ve olgun bir sperm h\u00fccresiyle sonu\u00e7lan\u0131r.<br>\u200b<br>Sperm \u00fcretiminin\/olgunla\u015fmas\u0131n\u0131n durdu\u011fu a\u015famaya ba\u011fl\u0131 olarak k\u00f6k h\u00fccre tedavisinde ba\u015far\u0131n\u0131n belirlenmesi \u00f6nemlidir. Sperm olgunla\u015fma sorunlar\u0131, i\u00e7sel germ h\u00fccre kusurlar\u0131na veya d\u0131\u015fsal somatik ve\/veya endokrin problemlere ba\u011flanabilir. Fark\u0131 bilmek, sorunun kesin hedefini belirlemenin anahtar\u0131 olabilir. Bununla birlikte, bu t\u00fcr hedefli tedavi \u015fu anda insan modelinde mevcut de\u011fildir. A\u015fa\u011f\u0131daki resim, spermatogenez s\u00fcrecinin g\u00f6rselle\u015ftirilmesine yard\u0131mc\u0131 olur: <\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"713\" src=\"https:\/\/www.lowcostivf.net\/wp-content\/uploads\/2020\/01\/stem-cell-therapy-1024x713.png\" alt=\"\" class=\"wp-image-3616\" srcset=\"https:\/\/www.lowcostivf.net\/wp-content\/uploads\/2020\/01\/stem-cell-therapy-1024x713.png 1024w, https:\/\/www.lowcostivf.net\/wp-content\/uploads\/2020\/01\/stem-cell-therapy-300x209.png 300w, https:\/\/www.lowcostivf.net\/wp-content\/uploads\/2020\/01\/stem-cell-therapy-768x535.png 768w, https:\/\/www.lowcostivf.net\/wp-content\/uploads\/2020\/01\/stem-cell-therapy-750x522.png 750w, https:\/\/www.lowcostivf.net\/wp-content\/uploads\/2020\/01\/stem-cell-therapy.png 1092w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>Mitoz, germ h\u00fccre hatt\u0131n\u0131n \u00e7o\u011fald\u0131\u011f\u0131 ve say\u0131ca b\u00fcy\u00fcd\u00fc\u011f\u00fc a\u015famad\u0131r. Farkl\u0131la\u015fma daha sonraki a\u015famalarda gelir. \u00d6rne\u011fin, e\u011fer spermatogenez, spermatitlerle sonu\u00e7lanacak a\u015famaya ula\u015fabilirse, o zaman as\u0131l mesele, bildi\u011fimiz \u015fekliyle sperm h\u00fccresine nihai farkl\u0131la\u015fmad\u0131r. Bu muhtemelen k\u00f6k h\u00fccre tedavisi i\u00e7in en uygun vakalardan biridir, \u00e7\u00fcnk\u00fc spermatogenez s\u00fcrecindeki yaln\u0131zca bir a\u015fama sorunludur ve sorunu ba\u015far\u0131yla \u00e7\u00f6zme olas\u0131l\u0131\u011f\u0131 daha y\u00fcksektir.&nbsp;<\/p>\n\n\n\n<p>Sorun erken a\u015famalardaysa ve olgunla\u015fmam\u0131\u015f sperm h\u00fccreleri \u00fcretilmiyorsa, g\u00f6rev daha zor hale gelir. Bu nedenle, spermatogenez s\u00fcrecinde ne kadar sorun ya\u015farsak, kulland\u0131\u011f\u0131m\u0131z herhangi bir m\u00fcdahalede ba\u015far\u0131 \u015fans\u0131 o kadar y\u00fcksek olur.<\/p>\n\n\n\n<p>&#8220;<strong>Yaln\u0131zca Sertoli h\u00fccresi<\/strong>\u201d sendromu, testis yap\u0131lar\u0131nda germ h\u00fccrelerinin olmad\u0131\u011f\u0131 ve sadece sertoli h\u00fccrelerinin bulundu\u011fu bir durumu ifade eder. Sertoli cell only sendromu konjenital veya kazan\u0131lm\u0131\u015f olabilir. Konjenital sertoli cell only sendromunda germ h\u00fccresi bulunmad\u0131\u011f\u0131ndan \u015fu anda \u00f6nerilebilecek bir tedavi y\u00f6ntemi yoktur. Bununla birlikte, durum edinilirse (klinefelter sendromu, kabakulak, radyasyona maruz kalma bunlardan birka\u00e7\u0131d\u0131r), o zaman durum tersine \u00e7evrilebilir ve k\u00f6k h\u00fccre tedavisi uygulanabilir.<\/p>\n\n\n\n<p>K\u00f6k h\u00fccre tedavisinin bir par\u00e7as\u0131 olarak <a href=\"https:\/\/www.lowcostivf.net\/tr\/\">Kuzey K\u0131br\u0131s T\u00fcp Bebek<\/a>, abdominal liposuction&#039;dan elde edilecek k\u00f6k h\u00fccreleri hastan\u0131n kendi ya\u011f dokusundan izole ediyoruz. Bu, bir cerrah taraf\u0131ndan ger\u00e7ekle\u015ftirilen k\u00fc\u00e7\u00fck \u00f6l\u00e7ekli bir ameliyatt\u0131r. Standart cerrahi prosed\u00fcrler uygulan\u0131r, bu da ameliyattan belirli bir s\u00fcre \u00f6nce ba\u015flayarak yiyecek ve i\u00e7ecek k\u0131s\u0131tlamas\u0131na uyulmas\u0131 anlam\u0131na gelir. Ameliyata uygunlu\u011funu do\u011frulamak i\u00e7in bir dizi test de yap\u0131yoruz. Bunlar olduk\u00e7a standart prosed\u00fcrlerdir.<\/p>\n\n\n\n<p>Liposuction i\u015flemi ile elde edilen ya\u011f dokusu daha sonra enzim ayr\u0131\u015ft\u0131rma ve di\u011fer bir\u00e7ok prosed\u00fcre tabi tutulur, b\u00f6ylece k\u00f6k h\u00fccreler ba\u015far\u0131l\u0131 bir \u015fekilde izole edilebilir. Bu esnada hastan\u0131n periferik kan \u00f6rne\u011finden elde edilecek trombositten zengin plazma (PRP) da ayr\u0131ca izole edilir. K\u00f6k h\u00fccreler k\u00fclt\u00fcr ortam\u0131na tabi tutulup tohumland\u0131ktan ve t\u00fcm i\u015flemler yap\u0131ld\u0131ktan sonra k\u00f6k h\u00fccre pop\u00fclasyonu ile PRP kombinasyonu testislerin farkl\u0131 yerlerinden testislere enjekte edilir.<\/p>\n\n\n\n<p>\u0130\u015flem sonras\u0131 iyile\u015fme s\u00fcrecine g\u00f6re ayn\u0131 g\u00fcn veya ertesi g\u00fcn hastaneden taburcu edilirsiniz. Etkilerini g\u00f6rmek i\u00e7in k\u00f6k h\u00fccre tedavisinden \u00fc\u00e7 ay sonra semen analizi yap\u0131lmas\u0131 gerekir. Spermatogenezi sa\u011flam olan ve ileri evrelerde sorun ya\u015fayan hastalarda, i\u015flemden yakla\u015f\u0131k 3 ay sonra ejak\u00fclatta canl\u0131 sperm h\u00fccrelerinin g\u00f6r\u00fclmesini bekliyoruz. Ejak\u00fclatta canl\u0131 sperm h\u00fccreleri g\u00f6zlemlenmezse, d\u00f6llenme i\u00e7in kullan\u0131labilecek olgunla\u015fan sperm h\u00fccrelerini aramak i\u00e7in bir TESE\/TESA prosed\u00fcr\u00fc planlan\u0131r. T\u00fcm tedavi yakla\u015f\u0131k 2-3 g\u00fcn s\u00fcrer (\u00f6n test, prosed\u00fcr\u00fcn kendisi ve iyile\u015fme s\u00fcresi). Bu, toplamda sadece 2-3 g\u00fcn K\u0131br\u0131s&#039;ta kalman\u0131z gerekece\u011fi anlam\u0131na gelir. <\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Azospermi i\u00e7in k\u00f6k h\u00fccre tedavisinin maliyeti nedir?<\/h2>\n\n\n\n<p>Bu i\u015flemin maliyeti, ameliyat \u00f6ncesi \u00f6n testler, ilgili t\u00fcm laboratuvar \u00e7al\u0131\u015fmalar\u0131 ve k\u00f6k h\u00fccre enjeksiyonu ile bir gece hastanede kalma dahil olmak \u00fczere 6.000 Euro&#039;dur. Tedavinizi planlamadan \u00f6nce gerekli testler ideal olarak kendi \u00fclkenizde yap\u0131l\u0131r ve bu \u00fccrete dahil de\u011fildir.<\/p>\n\n\n\n<p>Bizim \u201chakk\u0131nda daha fazla bilgi bulacaks\u0131n\u0131z.<a href=\"\/tr\/stem-cell-therapy-for-azoospermia\/\">Obstr\u00fcktif Olmayan Azospermi \u0130\u00e7in K\u00f6k H\u00fccre Tedavisi<\/a>&quot; sayfa.<\/p>\n\n\n\n<p>L\u00fctfen <a href=\"\/tr\/contact\/\">hasta koordinat\u00f6rlerimizle ileti\u015fime ge\u00e7in<\/a> daha fazla bilgi i\u00e7in! <\/p>","protected":false},"excerpt":{"rendered":"<p>Sperm \u00dcretiminde K\u00f6k H\u00fccre Tedavisi? Obstr\u00fcktif olmayan azospermi, benzer sonu\u00e7lara yol a\u00e7an bir grup sorunu i\u00e7erir: Sperm \u00fcretimi\/olgunla\u015fmas\u0131n\u0131n olmamas\u0131. Sperm h\u00fccresinin \u00fcretimi ve olgunla\u015fmas\u0131yla ilgili t\u00fcm s\u00fcre\u00e7lerin toplam\u0131 i\u00e7in kullan\u0131lan bir terim olan spermatogenez, birden fazla a\u015famadan olu\u015fur. Bu ad\u0131mlardan herhangi biri s\u0131ras\u0131nda herhangi bir ar\u0131za [\u2026]<\/p>","protected":false},"author":2,"featured_media":3617,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[124],"tags":[126,125,123],"class_list":["post-3615","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-stem-cell-therapy","tag-stem-cell-for-nonobstructive-azoospermia","tag-stem-cell-sperm-2020","tag-stem-cell-therapy-for-azoospermia"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.3 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Stem Cell Therapy for Patients With Non-Obstructive Azoospermia<\/title>\n<meta name=\"description\" content=\"Stem cells can be used in sertoli cell only syndrome if the condition is acquired rather than congenital. 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