{"id":6173,"date":"2020-07-24T22:16:20","date_gmt":"2020-07-24T22:16:20","guid":{"rendered":"https:\/\/www.lowcostivf.net\/?p=6173"},"modified":"2020-07-24T22:52:19","modified_gmt":"2020-07-24T22:52:19","slug":"ovarian-prp-treatment","status":"publish","type":"post","link":"https:\/\/www.lowcostivf.net\/es\/latest-news-from-north-cyprus-ivf-center\/ovarian-prp-treatment\/","title":{"rendered":"Tratamiento PRP Ov\u00e1rico"},"content":{"rendered":"

La aplicaci\u00f3n de PRP ov\u00e1rico es un procedimiento en el que los componentes de la sangre del propio paciente se procesan y se inyectan en la corteza ov\u00e1rica con el fin de iniciar\/apoyar el proceso de ovog\u00e9nesis. Con los desarrollos recientes en im\u00e1genes m\u00e9dicas y pr\u00e1cticas de laboratorio, ha salido a la luz la existencia de c\u00e9lulas madre ov\u00e1ricas. Se ha demostrado que estas c\u00e9lulas madre ov\u00e1ricas tienen potencial para la ovog\u00e9nesis, el embarazo y el nacimiento vivo. Inicialmente, los modelos animales proporcionaron evidencia de dicho potencial, mientras que los modelos humanos posteriores mostraron la reanudaci\u00f3n de los ciclos menstruales en mujeres menop\u00e1usicas, la mejora de la funci\u00f3n ov\u00e1rica y el crecimiento y desarrollo de los ovocitos. Con las aplicaciones de PRP ov\u00e1rico, hay una serie de consideraciones que son importantes para un resultado exitoso:<\/p>\n\n\n\n

1- Concentraci\u00f3n de plaquetas<\/strong>: El plasma rico en plaquetas es la parte de nuestra sangre que tiene mayor contenido de plaquetas en comparaci\u00f3n con el resto de nuestra sangre. Con las aplicaciones de PRP ov\u00e1rico, concentramos los n\u00fameros de plaquetas en su plasma y elevamos los n\u00fameros ya altos hasta 5 veces su valor normal. Medimos su recuento de plaquetas antes y despu\u00e9s del procesamiento de plasma en nuestros laboratorios y ponemos los resultados a disposici\u00f3n de nuestros pacientes para que puedan ver por s\u00ed mismos cu\u00e1nto ha aumentado el contenido de plaquetas.<\/p>\n\n\n\n

2- Protocolos de inactivaci\u00f3n\/activaci\u00f3n<\/strong>: Las plaquetas pueden activarse puntualmente durante el trabajo de laboratorio. Necesitamos cronometrar su activaci\u00f3n para que se activen dentro de los ovarios, no antes. Por lo tanto, este paso es uno de los pasos m\u00e1s vitales que determinan el destino de las plaquetas.<\/p>\n\n\n\n

3- Sitio de inyecci\u00f3n<\/strong>: Las c\u00e9lulas madre ov\u00e1ricas se encuentran en partes espec\u00edficas de los ovarios. Apuntar a estos tejidos es importante para un tratamiento efectivo.<\/p>\n\n\n\n

\"\"<\/figure><\/div>\n\n\n\n

4- Suplementaci\u00f3n post-PRP<\/strong>: Las plaquetas contienen factores de crecimiento, enzimas, cofactores y muchas otras prote\u00ednas. Todos estos est\u00e1n involucrados en una serie de eventos fisiol\u00f3gicos, incluido el crecimiento y la proliferaci\u00f3n celular. Dado que nuestro objetivo es iniciar\/apoyar la ovog\u00e9nesis (desarrollo y maduraci\u00f3n de los ovocitos), necesitamos todo el apoyo biol\u00f3gico que podamos obtener. PRP es un componente clave para proporcionar este apoyo. Sin embargo, existen otros componentes que desempe\u00f1an un papel en el desarrollo celular, as\u00ed como en la integridad gen\u00e9tica de los procesos celulares. Uno de ellos es la hormona del crecimiento.<\/p>\n\n\n\n

La hormona del crecimiento humano es una hormona producida naturalmente en nuestros cuerpos que apoya el crecimiento y desarrollo celular. A medida que envejecemos, la producci\u00f3n tambi\u00e9n se ralentiza. Despu\u00e9s del tratamiento con PRP ov\u00e1rico, nuestro objetivo es iniciar la producci\u00f3n de ovocitos y la hormona del crecimiento humano ayuda a apoyar el crecimiento del proceso de ovog\u00e9nesis. Para esto, recomendaremos un uso de 10 semanas de suplementos de hormona de crecimiento humana en dosis bajas. Se ha demostrado en nuestra propia experiencia cl\u00ednica que HGH mejora la integridad gen\u00e9tica de los ovocitos cuando se administra en dosis bajas aproximadamente durante 10 semanas antes de la recolecci\u00f3n de ovocitos. La eficacia y el uso de la hormona del crecimiento est\u00e1n bien informados en los tratamientos de FIV. Sin embargo, es puramente nuestro propio protocolo usar la hormona del crecimiento humano junto con el PRP ov\u00e1rico, que es esencialmente el mismo principio. A continuaci\u00f3n hay un enlace a algunas investigaciones recientes sobre esto:

https:\/\/www.frontiersin.org\/articles\/10.3389\/fendo.2019.00502\/full<\/a>
https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/29264990<\/a><\/p>\n\n\n\n

Tambi\u00e9n se ha demostrado que el uso de suplementos de mioinositol mejora la calidad de los ovocitos en las que responden mal. Se ha demostrado que el mioinositol mejora el recuento y la calidad de los ovocitos cuando se usa durante al menos 6 semanas antes del tratamiento de FIV. En este contexto, lo usamos como terapia adjunta para apoyar el proceso de ovog\u00e9nesis durante aproximadamente 3 meses antes del procedimiento de recolecci\u00f3n de \u00f3vulos (desde el momento del PRP ov\u00e1rico hasta el momento en que recolectamos los \u00f3vulos durante el ciclo de FIV). A continuaci\u00f3n se muestran algunos estudios publicados que muestran los efectos de la suplementaci\u00f3n con inof\u00f3licos antes de un ciclo de FIV:

https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4464995\/<\/a>
https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5350329\/<\/a><\/p>\n\n\n\n

Los pacientes en grupos de edad m\u00e1s j\u00f3venes tienden a beneficiarse a\u00fan m\u00e1s de la aplicaci\u00f3n de PRP ov\u00e1rico, ya que todav\u00eda tienen una gran cantidad de fol\u00edculos primordiales. Incluso cuando hay un problema con la ovulaci\u00f3n, a menudo es posible estimular los fol\u00edculos primordiales en la l\u00ednea de fol\u00edculos preantrales y antrales e iniciar la ovulaci\u00f3n. Esto hace que los fol\u00edculos primordiales sean nuestro objetivo principal cuando tratamos a pacientes en grupos de edad m\u00e1s j\u00f3venes. Vemos resultados mejores y m\u00e1s r\u00e1pidos en pacientes menores de 40 a\u00f1os que tienen insuficiencia ov\u00e1rica prematura.<\/p>\n\n\n\n

\"\"<\/figure><\/div>\n\n\n\n

Las OSC (c\u00e9lulas madre ov\u00e1ricas) requieren factores de crecimiento para diferenciarse en la l\u00ednea de c\u00e9lulas germinales. Una vez que ocurre la diferenciaci\u00f3n, siguen el camino de la ovog\u00e9nesis. De manera similar, los fol\u00edculos primordiales, que ya est\u00e1n diferenciados de la l\u00ednea de c\u00e9lulas germinales, se reclutan directamente en los fol\u00edculos preantrales y antrales.<\/p>\n\n\n\n

Despu\u00e9s del tratamiento con PRP ov\u00e1rico, hemos observado la reanudaci\u00f3n espont\u00e1nea de los ciclos menstruales despu\u00e9s de la menopausia, los embarazos espont\u00e1neos con concepci\u00f3n natural y los embarazos de FIV. Dado que a\u00fan no estamos seguros de cu\u00e1nto tiempo es probable que duren los efectos completos, tratamos de planificar el tratamiento en un cronograma muy estricto para ejercer los efectos completos de nuestros tratamientos. Para ello, inmediatamente despu\u00e9s de una aplicaci\u00f3n de PRP, proporcionamos a nuestros pacientes un calendario para tomar suplementos y para un ciclo de FIV posterior. Requerimos dos juegos de pruebas hormonales. Una serie antes del tratamiento con PRP y una serie dos meses y medio despu\u00e9s del tratamiento con PRP. Por lo general, solicitamos que estas pruebas se realicen en el mismo laboratorio para mantener la coherencia de los resultados. El prop\u00f3sito de los resultados de estas pruebas es comparar los resultados antes y despu\u00e9s para que podamos ver por nosotros mismos qu\u00e9 tan exitoso ha sido el procedimiento. Seg\u00fan los resultados de las pruebas, avanzamos con la planificaci\u00f3n del tratamiento de FIV. El per\u00edodo de tiempo entre la aplicaci\u00f3n de PRP y la extracci\u00f3n de \u00f3vulos en un ciclo de FIV es de 75 a 120 d\u00edas, seg\u00fan la edad, el perfil previo al PRP y las pruebas posteriores al PRP.<\/p>\n\n\n\n

\"\"<\/figure><\/div>\n\n\n\n

Somos una de las primeras cl\u00ednicas del mundo en iniciar esta aplicaci\u00f3n y sabemos muy bien que la aplicaci\u00f3n de PRP ov\u00e1rico no es una mera inyecci\u00f3n de PRP en los ovarios. Es necesario un tratamiento bien dise\u00f1ado para apreciar todos los efectos de este innovador m\u00e9todo cient\u00edfico.<\/p>","protected":false},"excerpt":{"rendered":"

La aplicaci\u00f3n de PRP ov\u00e1rico es un procedimiento en el que los componentes sangu\u00edneos del propio paciente se procesan y se inyectan en la corteza ov\u00e1rica con el fin de iniciar\/apoyar el proceso de ovog\u00e9nesis. Con los recientes avances en im\u00e1genes m\u00e9dicas y en las pr\u00e1cticas de laboratorio, ha salido a la luz la existencia de c\u00e9lulas madre de ovario. Estas c\u00e9lulas madre de ovario [\u2026]<\/p>","protected":false},"author":2,"featured_media":6180,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[54],"tags":[80,130],"class_list":["post-6173","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-infertility-treatment","tag-ivf-over-40","tag-ovarian-prp-treatment"],"yoast_head":"\nOvarian PRP Treatment - North Cyprus IVF<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.lowcostivf.net\/es\/latest-news-from-north-cyprus-ivf-center\/ovarian-prp-treatment\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Ovarian PRP Treatment - North Cyprus IVF\" \/>\n<meta property=\"og:description\" content=\"Ovarian PRP application is a procedure in which a patient\u2019s own blood components are processed and injected into the the ovarian cortex for the purpose of initiating\/supporting the process of oogenesis. 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